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A Randomized Phase III Study of Neoadjuvant Chemotherapy Followed by Surgery Versus Surgery Alone for Patients With High Risk RetroPeritoneal Sarcoma (RPS)

What is this study?

This study is looking at a specific type of soft tissue cancer located in the back of the abdomen. Researchers want to see if giving cancer-fighting medicine before surgery helps patients live longer and stay cancer-free compared to having surgery alone.

Who can participate?

You might be eligible if you have a newly diagnosed, high-risk liposarcoma or leiomyosarcoma in your abdomen that has not spread to other parts of the body. You also must not have received prior treatments like radiation or major surgery for this cancer.

What will happen?

After you join, you will be randomly placed into one of two groups by chance. One group will have surgery right away, while the other group will receive chemotherapy before having their surgery.

Where and when?

This study is currently recruiting patients at multiple medical centers across locations including Alabama, Arizona, and California in the United States.

Key Points
  • 1Testing if chemotherapy before surgery improves outcomes for abdominal sarcoma
  • 2Patients are randomly assigned to either surgery alone or chemotherapy followed by surgery
  • 3The study is currently open and actively looking for participants

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Conditions Studied
This study is investigating treatments for the following conditions
Retroperitoneal SarcomaLiposarcomaLeiomyosarcoma

This summary was generated using AI and may not capture all details. Always consult with a healthcare professional for medical advice.