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Recruiting

Phase I/II, Multi-Center, Open-Label Study of VT3989, Alone or in Combination, in Patients With Locally Advanced or Metastatic Solid Tumors

What is this study?

This study is testing an experimental medicine called VT3989 to see if it can safely and effectively treat advanced solid tumors, including mesothelioma and certain lung cancers. Researchers want to see if this new drug works better on its own or when combined with existing cancer treatments to help patients who have run out of standard options.

Who can participate?

This trial is looking for adults with certain solid tumors or mesothelioma that have spread or cannot be removed by surgery. You may be eligible if your liver, kidneys, and bone marrow are healthy, and your cancer can be clearly seen on medical scans.

What will happen?

Participants will receive the study drug daily, either alone or in combination with other approved cancer therapies. You will be closely monitored by a medical team to track your health and see how your body responds to the treatment.

Where and when?

The study is currently recruiting patients at research centers in San Francisco, Chicago, and Boston. Please talk to your oncologist to see if one of these locations is right for you.

Key Points
  • 1Tests a new approach for patients whose cancer has not responded to or does not have standard treatments.
  • 2Combines the new drug VT3989 with established treatments like immunotherapy or targeted therapy.
  • 3Participants receive regular check-ups to ensure the drug is safe and well-tolerated.

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Conditions Studied
This study is investigating treatments for the following conditions
Solid Tumor, AdultMesotheliomaNSCLC

This summary was generated using AI and may not capture all details. Always consult with a healthcare professional for medical advice.