Phase 1/2 Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors
This study is testing a new experimental treatment called mRNA-4359 to see if it can help your immune system better recognize and fight advanced cancer. Researchers want to find out if this therapy works best on its own or when combined with other existing immunotherapy drugs.
This trial is for adults with advanced melanoma or non-small cell lung cancer that has spread or is difficult to remove. You must have already tried some standard treatments, and your doctors will need to verify specific details about your tumor's biology.
You will receive the study medication, either alone or in combination with other approved immune-boosting drugs. The medical team will closely monitor you to check for safety and see how your body and your cancer respond to the treatment.
The study is currently recruiting patients at medical centers in Los Angeles and San Francisco, California, as well as Aurora, Colorado. Please talk to your oncologist to see if your specific health history makes you a good fit for one of these locations.
- 1This is an early-stage study focused on safety and finding the right treatment approach.
- 2The therapy uses mRNA technology designed to 'teach' your immune system to identify cancer cells.
- 3Participants must be generally healthy enough to tolerate treatment and must not have certain pre-existing conditions like active brain tumors.
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Suggest a linkThis summary was generated using AI and may not capture all details. Always consult with a healthcare professional for medical advice.