Phase 1/2 Study of Rina-S in Patients With Locally Advanced and/or Metastatic Solid Tumors

This clinical trial is testing a new medication called Rina-S to see how safe it is and how well it works against various solid tumor cancers, including ovarian, lung, and breast cancers. By combining this new drug with other known treatments, researchers hope to find better ways to fight cancers that have spread or are difficult to treat with standard methods.

This study is designed for adults who have specific types of advanced or hard-to-treat solid tumor cancers that have not responded well to previous standard therapies. To join, your cancer must be measurable through imaging tests, and you must meet certain health requirements regarding your lung health and prior medication history.

If you join, you will receive the experimental drug Rina-S, often in combination with other medicines like chemotherapy or immunotherapy designed to attack cancer cells or support your immune system. You will be closely monitored by a medical team through regular appointments and scans to track how the treatment is working and how you are feeling.

This study is currently recruiting new participants and is being conducted at medical centers in Phoenix and Tucson, Arizona, as well as in Los Angeles, California.