A Phase 1 Study of ASP1002 in Participants With Metastatic or Locally Advanced Solid Tumors

This study is testing a new experimental treatment called ASP1002, which is designed to help your immune system find and attack solid tumors. By attaching to a specific protein on the tumor cells, it aims to help your body fight cancer that has already spread or could not be removed by surgery.

This study is looking for adults with specific types of advanced solid tumors, such as lung, colorectal, prostate, ovarian, or breast cancer. Participants must have already tried standard treatments or chosen not to, and meet certain health criteria regarding their heart and immune system.

You will receive the study medication through an infusion, which means it is given slowly through a tube into your vein every few weeks. Throughout the study, you will have regular clinic visits, physical exams, and imaging scans to see how you and your tumor are responding to the treatment.

The study is currently recruiting patients at medical centers in New Haven and Plainville, Connecticut, as well as Gainesville, Florida. It is an early-stage study, meaning doctors are still learning how to best use this new treatment safely.