A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome With Moderate-to-severe Systemic Disease Activity

This study is testing an experimental medication called dazodalibep to see if it safely helps people with Sjögren's syndrome, an immune system disorder that causes severe dryness. Researchers want to know if the medicine can calm the immune system and improve overall health and daily symptoms.

You might be eligible if you have been officially diagnosed with Sjögren's syndrome, have active symptoms despite your current treatments, and test positive for specific immune proteins in your blood. There are certain health exclusions, such as a recent history of cancer, blood clots, or certain active infections.

During the study, participants receive either the real experimental medication or a placebo, which looks like the medicine but contains no active ingredients. Researchers will closely monitor your safety, side effects, and how well the treatment manages your symptoms and overall disease activity.

This study has locations in places like Avondale, Chandler, and Flagstaff in Arizona, United States. The study status is currently completed, meaning participant visits and treatments have wrapped up.