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A Phase 1, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of the Oral Cyclin A/B-RxL Inhibitor CID-078 in Patients With Advanced Solid Tumor Malignancies

What is this study?

This study is testing a new experimental pill called CID-078 to see if it is safe and effective for patients with advanced solid tumors. It is a 'Phase 1' trial, which means researchers are primarily looking to learn how the drug works in the human body for the first time.

Who can participate?

This trial is for adults 18 and older with advanced solid tumors, such as breast or lung cancer, that have not responded to or have worsened after standard treatments. You must have a tumor that can be measured by medical scans and meet specific genetic requirements to be considered.

What will happen?

If you join, you will take the experimental medication CID-078 as your primary treatment. The research team will closely monitor your health to see how your body reacts to the medication and check if it helps slow down or stop the growth of your cancer.

Where and when?

The study is currently recruiting volunteers at medical centers in Sarasota, Florida; Boston, Massachusetts; and Grand Rapids, Michigan. Because this is a clinical trial, you should discuss with your doctor whether traveling to one of these sites is feasible for you.

Key Points
  • 1This is an early-stage study testing a new pill to treat advanced cancers.
  • 2Participants must have advanced cancer that has not responded to standard therapies.
  • 3The research team will closely track your safety and any potential side effects throughout the study.

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Conditions Studied
This study is investigating treatments for the following conditions
Advanced Solid TumorMetastatic Solid TumorRefractory Solid TumorCancerLung CancerTriple Negative Breast CancerBreast NeoplasmsNeuroendocrine TumorsNeuroendocrine CarcinomaRB1 Gene Mutation

This summary was generated using AI and may not capture all details. Always consult with a healthcare professional for medical advice.