Atovaquone Combined With Radiation in Children With Malignant Brain Tumors
This study is testing if adding a medication called atovaquone to standard radiation therapy helps treat aggressive brain tumors in children. The goal is to see if this combination is safe and helps doctors find better ways to fight these difficult cancers.
This trial is for children diagnosed with specific high-grade brain tumors, including glioma or medulloblastoma. To join, children must weigh at least 22 pounds, have stable health, and be able to perform daily activities without too much difficulty.
Participants will receive the study medication (atovaquone) along with their scheduled radiation treatment. Doctors will closely monitor the children to see how well they tolerate the combination and to check for any potential side effects.
The study is currently recruiting patients and is taking place at locations in Atlanta, Georgia. Because this is a clinical trial, your medical team will provide specific details on the timeline for your child.
- 1The study combines a known medication with radiation to improve cancer treatment outcomes.
- 2Safety is the primary focus of this early-stage research.
- 3Participation requires meeting specific physical and neurological health criteria, such as having stable seizure control.
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