Chronic Convection Enhanced Delivery of Topotecan for Recurrent Malignant Glioma
This study is testing a new way to treat brain tumors that have come back after standard therapy. By using a special pump to deliver chemotherapy directly to the brain, researchers hope to fight the cancer more effectively while keeping the patient safe.
This study is for adults with a specific type of recurring brain tumor (IDH-mutated) that has stopped responding to standard treatments. You must be able to perform daily activities on your own and be healthy enough for a surgical procedure.
A small pump will be placed under your skin, connected to a tiny tube that delivers medicine directly to your tumor over several weeks. During this time, you will have regular check-ups, blood tests, and scans, and at the end, the pump will be removed along with the tumor.
This study is currently recruiting participants in New York City, New York.
- 1The treatment uses a specialized pump to deliver chemotherapy directly to the brain site.
- 2Participants will be closely monitored with regular medical exams and imaging throughout the treatment.
- 3This trial specifically looks at patients whose recurring brain tumors have a certain genetic marker known as the IDH mutation.
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