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Recruiting

A First-In-Human (FIH) Phase I/II Open-label, Multicentre, Dose Escalation and Expansion Trial of VERT-002 in Patients With Locally Advanced or Metastatic Solid Tumors Including Non-small Cell Lung Cancer (NSCLC) Harboring Mesenchymal-Epithelial Transition (MET) Alterations

What is this study?

This study is testing a new experimental drug called VERT-002 to see if it is safe and effective for patients with solid tumors. It focuses on cancers that have a specific genetic change in the MET gene, which helps doctors target the cancer more precisely.

Who can participate?

You may be eligible if you have an advanced solid tumor or non-small cell lung cancer that hasn't responded to standard treatments. You must also have specific MET gene changes that have been confirmed by lab testing.

What will happen?

Participants will receive the experimental medication VERT-002 under close medical supervision to determine the safest and most effective dose. You will have regular check-ups with the research team to monitor your health and how the cancer responds to the treatment.

Where and when?

This study is currently recruiting patients at locations in Washington D.C., Ohio, and Tennessee. Please consult with your doctor to see if one of these centers is a good fit for your needs.

Key Points
  • 1This is a Phase 1/2 study, meaning researchers are testing both the safety and potential benefits of the drug.
  • 2It is specifically designed for people whose cancers have certain MET gene mutations.
  • 3Participation requires careful screening to ensure the trial is the right match for your specific type of cancer.

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Conditions Studied
This study is investigating treatments for the following conditions
Solid TumorMET Alteration

This summary was generated using AI and may not capture all details. Always consult with a healthcare professional for medical advice.