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Recruiting

Evaluation of Digoxin for Relapsed Non-WNT, Non-SHH Medulloblastoma

What is this study?

This study is testing if a medication called digoxin can help treat a specific type of recurring brain cancer called medulloblastoma. Because this cancer has come back after previous treatments, doctors are looking for new ways to fight it in children and young adults.

Who can participate?

This trial is for patients aged 1 to 29 who have been diagnosed with a specific subtype of medulloblastoma that has returned after chemotherapy and radiation. You must have finished recent treatments and be stable enough to participate.

What will happen?

Participants will receive digoxin, a medication typically used for heart conditions, to see how it affects their tumor. The medical team will closely monitor your health and how your body responds to the treatment throughout the study.

Where and when?

The study is currently recruiting patients at locations in Birmingham, Alabama; Little Rock, Arkansas; and Hartford, Connecticut. Please check with your doctor to see if one of these locations is right for you.

Key Points
  • 1This is a Phase 2 study evaluating a new use for an existing medication.
  • 2Patients must meet specific medical history requirements, including previous rounds of cancer therapy.
  • 3Participants cannot take other experimental cancer drugs while enrolled in this trial.

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Conditions Studied
This study is investigating treatments for the following conditions
MedulloblastomaMedulloblastoma, Non-WNT/Non-SHH

This summary was generated using AI and may not capture all details. Always consult with a healthcare professional for medical advice.