WeTrials
Recruiting

ICON-RT: Intracranial Consolidation and Deferral of Radiation Therapy in Patients Receiving Approved CNS-Active Systemic Therapeutics

What is this study?

This study looks at the best way to treat lung cancer that has spread to the brain. It compares using a targeted medication alone versus using that medication alongside a precise form of radiation to see which approach provides the best results for patients.

Who can participate?

You may be eligible if you are 18 or older and have non-small cell lung cancer with a specific genetic mutation called an EGFR mutation. You must have brain tumors that are currently stable and have not previously received radiation to the brain.

What will happen?

Participants will take a daily cancer-fighting pill and may receive targeted radiation therapy, depending on which study group they are in. You will also complete regular questionnaires so the research team can understand how the treatment affects your daily quality of life.

Where and when?

The study is currently recruiting patients at locations in Miami, Florida, and Basking Ridge and Middletown, New Jersey. Please check with your doctor to see if one of these centers is a good fit for your care.

Key Points
  • 1Tests if precise radiation after starting medication improves outcomes.
  • 2Uses a targeted pill that blocks proteins to slow cancer growth.
  • 3Focuses on maintaining your comfort and quality of life throughout the study.
  • 4Requires participants to have stable brain tumors and specific genetic markers.

No related links yet

Seen this study covered in the news, or found a page that explains it well? Send it over and we'll review it.

Suggest a link
Conditions Studied
This study is investigating treatments for the following conditions
Non Small Cell Lung Cancer Metastatic

This summary was generated using AI and may not capture all details. Always consult with a healthcare professional for medical advice.