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A Phase 2 Trial of SX-682 and Atezolizumab in Patients With Advanced NSCLC Who Progressed on Prior Chemotherapy and Immune Checkpoint Inhibitor (ICI) Therapy

What is this study?

This study is testing a combination of two drugs, SX-682 and atezolizumab, for people with advanced non-small cell lung cancer. Researchers want to see if this combination can help the body's immune system fight the cancer after other treatments have stopped working.

Who can participate?

Adults 18 and older with advanced lung cancer that has spread, returned, or cannot be treated with surgery can join. Participants should not have certain gene mutations like EGFR or ALK, and must meet specific health and treatment history requirements.

What will happen?

Participants will receive the study medications, which include an experimental drug and an immunotherapy treatment. Throughout the study, doctors will monitor your health using imaging scans like CT and MRI, and collect routine blood and tissue samples.

Where and when?

This study is currently recruiting patients and takes place in Seattle, Washington, United States. If you are nearby and meet the health criteria, your care team can help you connect with the study location.

Key Points
  • 1Tests a new drug combination for advanced lung cancer
  • 2Aims to boost the immune system to fight tumor cells
  • 3Currently recruiting patients in Seattle, Washington

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Conditions Studied
This study is investigating treatments for the following conditions
Advanced Lung Non-Small Cell CarcinomaMetastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8Stage IV Lung Cancer AJCC v8

This summary was generated using AI and may not capture all details. Always consult with a healthcare professional for medical advice.