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A First-in-human Study of RLY-8161 for Treatment of Advanced NRAS-Mutant Melanoma and Other Solid Tumors

What is this study?

This study is testing a new experimental drug called RLY-8161 for people with advanced skin cancer and other solid tumors. It is designed to target specific changes in the NRAS gene that help cancer grow, with the goal of finding a safe and effective new treatment option.

Who can participate?

You may be able to join if you have advanced skin cancer or another solid tumor with a confirmed NRAS gene change where standard treatments have not worked. Participants must also be able to carry out their normal daily activities.

What will happen?

As a participant, you will receive the investigational medication RLY-8161 and have your health closely monitored with regular scans and check-ups. The study team will track how your body responds to the drug and check for any side effects.

Where and when?

This study is currently recruiting patients at multiple medical centers, including locations in Los Angeles and San Francisco, California, as well as Aurora, Colorado.

Key Points
  • 1Testing a new targeted cancer drug named RLY-8161
  • 2For patients with advanced tumors containing specific NRAS gene changes
  • 3Currently recruiting participants at select locations in the United States

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Conditions Studied
This study is investigating treatments for the following conditions
Advanced NRAS-Mutant MelanomaAdvanced NRAS-Mutant Solid TumorsNRAS MutationNRAS G12DNRAS G13RNRAS G13DNRAS G12VNRAS Q61RNRAS Q61KNRAS Q61LNRAS Q61H

This summary was generated using AI and may not capture all details. Always consult with a healthcare professional for medical advice.